SARS-CoV-2 and COVID-19 Preprints

SARS-CoV-2 and

COVID-19 Preprints

Ultrastructural morphology exhibited by coronaviruses.
CDC/ Alissa Eckert, MS; Dan Higgins, MAM

Since November 2019, the novel coronavirus known as SARS-CoV-2 (formerly, 2019-nCoV) has devastated communities and overwhelmed healthcare facilities worldwide. Research on the virus, its epidemiology, modes of infection, and potential treatments has been rapid, providing new insights to guide both clinical practice and public health recommendations each day.

The ability to share discoveries quickly is at the heart of the preprint mission, and facilitating it has been central to the ethos of Research Square since its founding. At no time is this goal more salient or pressing than in times of public health emergencies. Here, we aim to provide the most recent Research Square preprints relevant to the COVID-19 outbreak and its wide-ranging effects on the global community. All content posted here is free to read and download, and we encourage readers to engage via comments and annotations.

Research Articleposted 2026-01-09 07:38:02

Adult Vaccination Status in the Elderly Population: A Cross-Sectional Evaluation

İLKNUR DEMİR, GÜZİN ZEREN ÖZTÜRK, Beray Gelmez Taş

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Research Articleposted 2026-01-09 03:19:20

Well-being, isolation, and lockdowns

José Ignacio Gimenez-Nadal, José Alberto Molina, Jorge Velilla

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Systematic Reviewposted 2026-01-08 05:49:08

The Role of Remote Sensing-based in Crop Yield Prediction: A Systematic Literature Review of Approaches, Data Sources, and Challenges

Soka Zimba, Aaron Zimba, Bob Jere

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Research Articleposted 2026-01-08 05:40:26

Novel graph attention autoencoder framework with multilayered validation identifies drug repurposing candidates for COVID-19 treatment

Yusuke Nakayama, Shingo Tsuji, Koji Yamamoto, Juran Kato-Suzuki, Kouichi Hosomi

Under Review

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Articleposted 2026-01-08 05:26:23

Persistent Immune Dysregulation during Long COVID is Manifested in Antibodies Targeting Envelope and Nucleocapsid Proteins

Jalees Rehman, Marcin Kwissa, Manikannan Mathayan, Satyajeet Salunkhe, Velavan Bakthavachalam, Zijing Ye, Mark Sanborn, and 23 more authors

Under Review

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Research Articleposted 2026-01-07 15:58:33

Changes in Antimicrobial Resistance of Staphylococci Isolated from Bloodstream Infection and the Impact of COVID-19

Yan Wu, Mengjun Zhou

Under Review

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Research Articleposted 2026-01-07 11:47:15

Adaptation Mechanisms of Hong Kong Secondary School Students to the Sudden Shift to Online Learning During the COVID-19 Pandemic: Path Analysis of PISA 2022 Data