Design
Retrospective cohort study
Time and location
The trial was conducted from June 2021 to March 2023 at the Department of Joint Surgery.
Inclusion criteria
① Diagnosed with femoral neck fracture based on preoperative anteroposterior and lateral X-ray images of the hip joint and CT three-dimensional reconstruction; ② Age ≥75 years old with complete clinical records; ③ Fresh fracture (time from injury to admission ≤7 days); ④ Garden classification type III or IV; ⑤ Preoperative assessment of bilateral lower limb motor function, sensory nerve conduction, and muscle strength showed no abnormalities; ⑥ All patients underwent posterior lateral approach hemiarthroplasty and were able to tolerate the surgical treatment method used in this study, and signed the relevant informed consent form.
Exclusion criteria
① Patients with underlying conditions such as severe heart, liver, or kidney dysfunction, or systemic malignant tumors that may lead to pathological fractures;② Patients with cognitive impairments who cannot cooperate with postoperative efficacy assessments (e.g., Alzheimer's disease, etc.); ③ Postoperative follow-up duration less than 12 months or missing critical data; ④ Concurrent fractures of the same-side lower limb or pelvis, active hip joint infection, prior hip joint surgery history, or developmental deformities; ⑤ Outerbridge grading of acetabular cartilage degeneration ≥ Grade III or radiologically confirmed Charcot joint disease; ⑥ Long-term use (continuous use ≥ 3 months) of corticosteroids or anticoagulant drugs within 1 year prior to surgery; ⑦ Bone density testing indicating severe osteoporosis (T-score ≤ -3.0 SD).
Participants and groups
A retrospective analysis was conducted on 124 elderly patients with unilateral femoral neck fractures who were admitted to the Department of Joint Surgery at the Hospital between June 2021 and March 2023. All enrolled patients underwent hemiarthroplasty via the posterolateral approach. Based on comprehensive clinical data and preoperative physician–patient communication, patients were allocated according to their preference into either the experimental group (n=65), which received anatomical biomimetic reconstruction of the external rotators combined with repair of the zona orbicularis, or the control group (n=59), which underwent conventional suture repair (fixation of the joint capsule and external rotator tendons to the greater trochanter). This study was approved by the institutional ethics committee of our hospital , and written informed consent was obtained from all participants.
Surgical method
Preoperative preparation
All patients underwent comprehensive imaging assessments upon admission to evaluate the acute/chronic nature and stability of fractures; Bone density assessment was used to evaluate bone quality; routine blood biochemical tests and 25-hydroxyvitamin D3 tests were performed, and tumor marker tests were conducted on all patients to assess their overall health status. Preoperative correction of anemia (iron supplements + EPO for patients with Hb < 90 g/L) and tranexamic acid administered in divided doses (1 g intravenous infusion 15 minutes before incision); the surgical site was covered with domestically produced 3M iodine film to prevent infection, and the prosthesis was provided by Tianjin Zhengtian Company .All surgical procedures were performed by the same senior attending surgeon in our department. Our institution has obtained the requisite certification to perform this specific technique.
Experimental group surgery method
Based on the patient's cardiopulmonary function and overall condition, spinal-epidural combined anesthesia is prioritized. General anesthesia is administered for patients with contraindications. Taking the right hip joint as an example, the patient is positioned in a lateral decubitus position. After routine disinfection and draping, a modified Gibson incision is made: Starting 5 cm distal to the iliac crest, the incision is made in an arc outward along the posterior border of the greater trochanter to the proximal femur. The subcutaneous tissue is incised layer by layer, and the gluteus maximus muscle fibers are bluntly dissected along their course to expose and protect the sciatic nerve. At the intertrochanteric crest, the attachment points of the external rotator muscle group, including the quadratus femoris muscle and the obturator internus and externus muscles, are transected. Expose the joint capsule. Incise the posterior joint capsule downward along the junction of the middle and outer thirds of the femoral neck at its attachment point on the femoral side. Do not perform any procedures on the acetabular side to preserve the labrum as much as possible. From this incision site, incise the joint capsule vertically along the acetabular margin, taking care to protect the labrum. Do not perform any special procedures on the posterior inferior portion of the joint capsule to maintain its integrity. The severed external rotator muscle group and joint capsule complex are folded back toward the muscle belly and temporarily fixed to the gluteus maximus fascia, forming a dynamic neural protective barrier to effectively prevent intraoperative traction injury to the sciatic nerve and its branches. The anteversion angle (15° ± 5°) is determined using a medullary cavity locator, and a graded medullary reaming technique is used to match the femoral prosthesis. After installing the trial model, assess lower limb length and joint stability. Once confirmed, implant the bone cement-type femoral stem. During acetabular side processing, ensure the tension of the external rotator muscle group-joint capsule complex is maintained to avoid excessive traction causing injury to the superior gluteal neurovascular bundle. Perform a stepwise four-point suture using absorbable sutures: the first suture is inserted vertically from the lateral margin of the piriformis fossa into the gluteus medius tendon, passing through and exiting from the medial side; the second suture is inserted from the opposite side of the wound margin, penetrating the tendinous tissue of the external rotator muscle group and the deep layer of the joint capsule from the outside to the inside; The third suture is inserted 1 cm from the previous suture in the opposite direction, penetrating from the inner layer of the joint capsule outward through the external rotator tendon membrane; the final suture is placed 1 cm from the third suture in the piriformis fossa region, vertically penetrating the gluteus medius tendon from the inside outward. After tying the suture, the external rotator tendon membrane complex is precisely anatomically repositioned slightly below the gluteus medius muscle and terminates near the piriformis fossa. Joint capsule reconstruction involves using high-strength tendon sutures to perform “edge-to-edge” anastomosis of the iliofemoral ligament and the annular ligament, restoring the integrity of the cylindrical structure of the joint capsule. After irrigation of the surgical field, the deep fascia, subcutaneous tissue, and epidermis are layered and sutured, with sterile dressings covering the wound.(Figure 1)
Control group surgery method
The control group underwent conventional posterior lateral approach total hip arthroplasty using conventional suturing techniques. The joint capsule and external rotator muscle tendons were woven together using high-strength tendon sutures, tested for tensile strength to rule out the possibility of avulsion, and then fixed to the greater trochanter. The remaining steps were the same as those in the experimental group.
Postoperative management
Postoperative continuous monitoring of hemodynamic parameters, routine thromboprophylaxis, sequential treatment with broad-spectrum antibiotics, NSAIDs combined with nerve block analgesia, proton pump inhibitors, and volume support protocols. For patients with lower limb swelling, vascular ultrasound angiography should be performed immediately to assess and rule out the possibility of embolism. If venous system abnormalities are confirmed, a multidisciplinary collaborative diagnosis and treatment mechanism should be initiated. Hemodynamic parameters should be dynamically monitored within 72 hours postoperatively. A tiered blood transfusion protocol should be implemented based on hemoglobin fluctuations (Hb < 100 g/L to assess transfusion indications, with transfusions administered as appropriate; Hb < 70 g/L for emergency transfusions). The affected limb should be immobilized in a neutral rotational position, and hip flexion-adduction-internal rotation composite movement patterns should be strictly restricted for 21 days postoperatively. Intermittent pneumatic compression therapy should be initiated 24 hours postoperatively to optimize venous return. The rehabilitation program is implemented in four progressive phases: isometric muscle strength training is initiated in the early perioperative period; after 48–72 hours postoperatively, protective weight-bearing with a walker is initiated following dynamic balance assessment; after 14 days, transition to crutch-assisted gait retraining; and by 4–6 weeks, achieve unassisted walking, concurrently establishing a protective joint range of motion training regimen.
Main Observation Indicators
(1)Perioperative-related indicators:Record the surgical duration, intraoperative blood loss, incision length, incision healing status, and hospital stay for both groups of patients.
(2)Efficacy evaluation indicators:Record the VAS scores, Harris scores, hip flexion-extension range of motion, internal rotation-external rotation range of motion, and time to full weight-bearing for both groups of patients at 1 month, 3 months, and 6 months postoperatively to evaluate clinical efficacy.Outcome data were prospectively collected by trained nursing staff through face-to-face interviews in the ward using standardized visual analog scale (VAS) and Harris Hip Score (HHS) instruments. Postoperative follow-up assessments were primarily conducted during outpatient visits. For patients unable to attend in-person appointments, structured telephone interviews or secure electronic questionnaire links were utilized to obtain VAS and HHS data. All assessors underwent standardized training to ensure inter-rater reliability. Loss to follow-up was documented to minimize attrition bias.
(3)Imaging-related indicators:Patients were followed up at regular outpatient visits at 1 month, 3 months, and 1 year postoperatively, with repeat X-rays of the affected hip joint in anteroposterior and lateral views, as well as pelvic X-rays. CT scans were performed as needed. Imaging studies were used to accurately measure the acetabular anteversion angle, abduction angle, and lower limb length, and to assess for prosthesis loosening or periprosthetic fractures.All radiographic assessments were independently performed by three attending physicians with the rank of associate chief or higher, all of whom were blinded to patient clinical information. To ensure reliability, the radiographic images were exchanged among the evaluators for a second round of independent review after the initial assessment. Any discrepancies in evaluation were resolved by a separate senior expert with advanced qualifications, thereby minimizing potential observer bias.
(4)Complication-related indicators:Closely monitor for dislocation or prosthesis-related infections during hospitalization and subsequent follow-up, and maintain detailed records.
Statistical analysis
Statistical analysis was performed using SPSS 27.0 software. The K-S test was used to assess the normality of continuous variables in the indicators. For data meeting the criteria for normal distribution, a two-sample t-test was conducted, with results expressed as mean ± standard deviation. Count data were presented as percentages, and intergroup comparisons were performed using the chi-square test; repeated measures data were analyzed using analysis of variance (ANOVA). All statistical analyses were performed using SPSS 27.0, with P < 0.05 considered statistically significant.The statistical methods and all results of this study were reviewed by a statistical expert at the Hospital .
Participant Analysis
A total of 130 patients with unilateral elderly femoral neck fractures were included and divided into two groups based on the method of posterior soft tissue repair of the hip joint: the experimental group (using anatomical biomimetic reconstruction of the external rotator muscle group combined with the iliotibial band repair, n=65) and the control group (using conventional suturing methods, n=59). Two and four patients in the experimental and control groups, respectively, were excluded due to incomplete follow-up data, resulting in 124 patients included in the final analysis.The flow chart of the two groupings is shown inFigure 2。