Mauritius island of the Indian Ocean, is not free from tsunami waves generated by converging tectonic plates. On 26th December 2004, tsunamis generated from the Sumatra Andaman earthquake caused a minor but noticeable inundation. The island is mainly dependent on its sandy beaches and blue lagoons as assets well publicized for the tourism sector. Eventually, the coastal region rapidly developed its infrastructures with major investments in hotels and luxurious villas. However, the major Mauritian economic spine becomes vulnerable towards significant sea surges occurring from cyclonic conditions or worst, a potential tsunami. This research study investigates upon the possible threat of tsunami waves striking the northern part of Mauritius region namely, Grand Bay coastal village. Emphasis was laid upon the vulnerability assessment of human lives due the dynamic flow of population with respect to time. The methodology includes digitalisation of the Grand Bay region with existing updated buildings, using the QGIS software from high resolution satellite raster images, followed by the input of geospatial and relative attributes data. Tsunamis sources of both Makran and Sumatra regions were considered with generations of waves from 4 metres to 16 metres reaching the Grand Bay coast. These were analysed in QGIS by weightage of spatial attributes set by professional votes through Intercept Surveys. Maps generated by QGIS showed an increase in vulnerability of human lives with higher probable casualties during weekends at Grand Bay. Around 40000 people are at risk for an 8m wave tsunami strike. Apart from delocalisation of the existing infrastructures, soft and hard solutions were proposed for specific regions to minimize the impact of a least tsunami threat.