Premature birth, taking place before the 37th week of pregnancy, remains a leading cause of infant health challenges and mortality worldwide. Parents often lack the necessary knowledge and support to adopt caregiving practices essential to improving outcomes for these vulnerable newborns—like sustained breastfeeding, proper maternal nutrition, and kangaroo care. This is especially true in underserved communities, where access to specialized neonatal care and parent education is limited. To address these challenges, a team of researchers and clinicians introduced the Pebbles of Hope Thrive Guide, an interactive course designed to empower mothers with the skills and confidence needed to support premature infant health both in the NICU and after discharge. A pilot study tested its effectiveness across 50 mothers of premature infants from 3 hospitals in the southern United States, finding it improved the mothers' confidence and knowledge. Users also reported an increase in kangaroo care, where caregivers provide skin-to-skin contact with their babies, reinforcing bonds and providing physiological benefits. However, the program did not significantly affect how many continued to provide breast milk to their infants at 3 months post partum. It also did not have any significant influence on behaviors surrounding maternal nutrition. While these results are promising, they underscore the need to identify strategies ensuring behavioral changes endure over the long term and to improve access to resources and support systems from healthcare providers, family and friends.