Research Articleposted 2025-12-31 10:39:30
A Randomized, Double-Blind, Controlled, Parallel Group Study with Amustaline/Glutathione Pathogen Reduced Red Blood Cells in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections (RedeS Study): -- Protocol for a Phase 3, Randomized, Controlled Trial
Edgardo F. Cartagena Ayala, Lumen Vera Colon, Yesim Aydinok, Bolívar Arboleda-Osorio, Arthur Bracey, Ross Fasano, Marianne Yee, and 17 more authors
Under Revision
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Research Articleposted 2025-12-30 01:20:13
Building Clinical Trials Capacity in a Developing Research Ecosystem
Eman Alsulmi
Under Review
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Research Articleposted 2025-12-25 09:07:22
Jejuno-Ileal and Jejuno-Colic Diversion as a New Bariatric Method in the Treatment of Diabetes and Obesity: Study Protocol for a Prospective Randomised Clinical Trial
Marek Buzga, Pavol Holeczy, Zdenek Svagera, Petr Svoboda, Vojtech Skop, Marek Vecka, Jana Rychlikova, and 3 more authors
Under Review
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Research Articleposted 2025-12-17 07:08:29
Effect of early dexamethasone on major complications and all-cause mortality in severe burns (DEXA-BURN): A multicenter, randomized, placebo-controlled, double-blind trial
Alexandre Bourdiol, Nicolas Bruder, François Dépret, Delphine Flattres, Laurent Flet, June Fortin, Anne-Emmanuelle Gaufichon, and 11 more authors
Under Revision
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Research Articleposted 2025-12-08 07:50:37
A randomized controlled study on the effects of the T-REX Twente (Thoracic Surgical Rehabilitation Experts Twente) sternal precautions on quality of life and physical activity levels in cardiac surgery patients, compared to standard care in patients following a median sternotomy: the study protocol
Nicole Wielens, Kim Roerdink, Winston Lynch, Lauren Esau, Job van der Palen, Frank Ruben Halfwerk
Under Review
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Research Articleposted 2025-12-08 07:49:18
Protocol for a phase 2, partially-blinded, randomised trial assessing the safety and efficacy of sorfequiline or bedaquiline, in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009)
Morounfolu Olugbosi, Maria Beumont, Leandra Lombard, Jerry Nedelman, Juliano Timm, Todd Black, Rebecca Bruning-Barry, and 10 more authors
Under Review
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Research Articleposted 2025-11-27 13:05:38
Effect of alpha-lipoic acid on atrial fibrillation and biomarkers of myocardial injury in patients undergoing coronary artery bypass surgery: Study protocol of a randomized, double-blind, placebo-controlled clinical trial
Rahil Salari-Baghoonabad, Soheil Mansourian, Elham Alipoor, Alireza Jahan-mihan, Motahareh Hatami, Mohammadhasan Ghasemi, Mehdi Yaseri, and 2 more authors
Under Review
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Research Articleposted 2025-11-25 18:39:23
The Effectiveness of Psychological Interventions for Common mental disorders (EPIC): Protocol of a pragmatic randomized waitlist-controlled superiority trial
Celia Faye Jacobsen, Carsten Hjorthøj, Ole Karkov Østergård, Stig Poulsen
Under Review
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Research Articleposted 2025-11-24 16:34:48
Improving aerobic capacity in patients with advanced non-small cell lung cancer: study protocol of the 3-armed randomized controlled BREATH trial
Nico De Lazzari, Marcel Wiesweg, Miriam Götte, Jan Franco, Raluca Ileana Mincu, Johannes Jäger, Eva-Maria Huessler, and 4 more authors
Under Review
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Research Articleposted 2025-11-24 08:35:42
Impact of Screen Failures on Enrollment Process and Patient Characteristics in Large-Scale Randomized Sham-Controlled Trial
Jingang Cui, Changdong Guan, Changpeng Song, Haobo Xu, Juan Wang, Yao Liu, Shengxian Tu, and 22 more authors
Under Review
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