Articleposted 2025-05-05 11:14:42
Targeting RhoA activity rejuvenates aged hematopoietic stem cells
Maria Carolina Florian, Eva Mejia-Ramirez, Pablo Iañez Picazo, Barbara Walter, Sara Montserrat-Vazquez, Francesco Affuso, Stefan Wieser, and 10 more authors
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Articleposted 2025-03-18 08:53:07
Large-scale Plasma Proteomic Profiling Unveils Novel Diagnostic Biomarkers and Pathways for Alzheimer's Disease
Armand Gonzalez-Escalante, Bin Zhang, David Bennett, Tammie Benzinger, Tony Wyss-Coray, Laura Ibanez, Yun Ju Sung, and 30 more authors
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Articleposted 2024-11-25 10:16:15
Allosteric activation of a cell-type specific GPR120 rescues cognition and extends lifespan of Alzheimer’s disease
Youming Lu, Aodi He, Yue Wang, Yuhang Shen, Zhiqiang Dong, Lingli Luo, Xiangyu Ge, and 8 more authors
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Articleposted 2024-10-30 03:39:03
Single-cell and spatial transcriptomics uncovers the role of senescent vascular cells in pathological arterial remodeling during murine atherosclerosis
Myriam Gorospe
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Articleposted 2024-08-20 05:20:35
A plasma proteomic signature links secretome of senescent monocytes to aging- and obesity-related clinical outcomes in humans
Nathan Basisty, Bradley Olinger, Reema Banarjee, Amit Dey, Dimitrios Tsitsipatis, Toshiko Tanaka, Anjana Ram, and 9 more authors
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Resourceposted 2024-07-24 09:27:41
A Unified Framework for Systematic Curation and Evaluation of Aging Biomarkers
Mahdi Moqri, Kejun Ying, Seth Paulson, Alec Eames, Alexander Tyshkovskiy, Siyuan Li, Martin Perez-Guevara, and 9 more authors
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Articleposted 2024-07-10 04:48:43
The Retrotransposon-Derived Capsid Genes PNMA1 and PNMA4 Maintain Reproductive Capacity
Seungsoo Kim, Blake Wiedenheft, Yousin Suh, Karen Schindler, Devanshi Jain, Binyam Mogessie, Vincenzo Gennarino, and 14 more authors
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Biological Sciences - Articleposted 2024-06-17 14:53:50
Body-to-brain Insulin and Notch signaling regulates memory through neuronal CREB activity
Coleen Murphy
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Articleposted 2024-05-30 01:20:04
Is 70 the new 60? A longitudinal analysis of cohort trends in intrinsic capacity in England and China
John Beard, Hanewald Katja, Yafei Si, Jotheeswaran Thiyagarajan, Dario Moreno-Agostino
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Articleposted 2024-03-28 03:09:24
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration
John Kornak, Alexander Pantelyat, Toji Miyagawa, Mario Mendez, Corey McMillan, Irene Litvan, Suzee Lee, and 61 more authors
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