Research Articleposted 2025-11-03 14:24:47
Synthesis of New Phosphonylated Bis-1,3,4-oxadiazoles and Study of Their Antimicrobial and Antiviral Activity
Elizaveta Gerasimova, Dmitry Egorov, Aleksandr Krylov, Ekaterina Chernova, Dar`ya Spiridonova, Irina Kuzikova, Tatyana Zaytseva, and 4 more authors
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Research Articleposted 2025-10-24 02:16:39
IND-Enabling Preclinical Studies of [11C]COU, a Trapped Metabolite PET Radiotracer for Monoamine Oxidase-B
Madison Frazier, Tanpreet Kaur, Jenelle Stauff, Wade P. Winton, Bradford D. Henderson, Alexandra S. Dumond, Xia Shao, and 5 more authors
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Research Articleposted 2025-09-17 19:21:16
Design, Synthesis and Biological Evaluation of Novel Hydroxamic Acids Bearing Coumarin Moieties as Histone Deacetylase Inhibitors and Cytotoxic Agents
Tran Duy Thanh, Luu Van Chinh, Do Thi Thao, Thach Lien Nguyen, Hai Pham–The, Tran Khac Vu
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Research Articleposted 2025-09-03 17:04:24
Disentangling the nonbonding interaction energy between KRAS oncoproteins and small-molecule non-covalent inhibitors helps clarifying how inhibition occurs
Francesco Pietra
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Research Articleposted 2025-08-20 14:18:01
Improving Conformational Stability and Bacterial Membrane Interactions of Antimicrobial Peptides with Amphipathic Helical Structure
Ahmad Habibie, Rizki Amalia Putri, Respati Tri Swasono, Endah Retnaningrum, Prajnaparamita Dhar, Krzysztof Kuczera, Tri Joko Raharjo, and 1 more authors
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Research Articleposted 2025-07-04 15:12:15
Triclosan is a pan-uridine 5'-diphospho-glucuronosyltransferase (UGT) and pan-cytochrome P450 (CYP) inhibitor with high selectivity towards CYP2C19
Guo Zhong, Megha Chandrashekhar, Theresa Aliwarga
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Research Articleposted 2024-11-19 10:58:59
Novel Conjugated 5-Alkenyl Rhodanine Tethered 1,4-Benzodioxane Derivatives as Dual-Chitinases Inhibitors to Hinder the Growth of Asian Corn Borer
Jinxiu Chen, Dongmei Shi, Zhiyang Jiang, Renxuan Zou, Jingyu Zhang, Qing Han, Na Wang, and 3 more authors
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Research Articleposted 2024-10-21 14:16:31
In vitro and in silico studies on α-glucosidase inhibitory properties of bioactive components from the rhizomes of Alpinia officinarum Hance
Zakhele Mphatsi Dlamini, Bongani Sicelo Dlamini, Shih-Han Fu, Ya-Lin Chang, Chi-Chien Lin, Yu-Kuo Chen, Kok-Tong Tan, and 1 more authors
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Research Articleposted 2024-10-16 08:42:14
Synthesis and Biological Assessment of Triazolo-Quinazoline Carbothioamide Derivatives for p38 MAP Kinase Inhibition: In-Silico and In-Vitro Approaches
Keerthi CH, Ramesh Kola, Divya Pingili, Archana Awasthi, DSNBK Prashanth, Kantlam Chamakuri
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Research Articleposted 2024-09-26 19:36:57
Design, synthesis and antitumor activity evaluation of Benzimidazole derivatives with potent HDAC inhibitory activity
Jiantao Ping, Hongrui Chu, Yisheng Zhao, Chen Chen
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