Articleposted 2025-12-25 19:47:43
Ubiquitin-Specific Peptidase 9X Inhibition for Antitumor Immunity Via Programmed Death Ligand 1 Ubiquitination and T-Cell Activation
Wei Chen, Tao Ma, Xiaoxiao Zheng, Ran Pan, Tianhao Nan, Li Zheng, Jiahua Lan, and 2 more authors
Under Review
at
Articleposted 2025-12-22 09:01:48
APOC3-Mediated Fatty Acid Metabolism Suppresses Lung Adenocarcinoma Progression by Inhibiting GNAI3/cAMP/PKA Pathway
Liping Dai, Feifei Liang, Ying Chen, Yihao Liang, Bing-Hua Jiang, Songyun Ouyang
Under Review
at
Articleposted 2025-12-17 09:25:00
mTORC1 Suppression by Trp53 Mutation Drives Resistance to Immune Checkpoint Blockade
Binfeng Lu, Alireza Labani-Motlagh, Yang Li, David Shihong Gao, Eunseuk Lee, Vincent Chen, Lixian Yi, and 7 more authors
Under Review
at
Articleposted 2025-12-15 01:07:46
Overcoming IGF1R-Mediated Resistance to Oncolytic HSV1 and Radiotherapy via Triple Combination Therapy
Ji Young Yoo, Alexandra Miller, Minhye Noh, Jin Muk Kang, Amanda Kouaho, Grace Nguyen, Minxin Huang, and 6 more authors
Under Review
at
Articleposted 2025-12-13 00:13:31
CASC19 co-operating with DHX9 Facilitates Gastric Cancer Progression and Metastasis through Inhibiting Ferroptosis and Promoting Immune Evasion
Weijian Guo, Sijie Sun, jinsi Chen, Wei Su, Yanqiu Zhang, Yanan Yang, Ting Zhao, and 1 more authors
Under Review
at
Articleposted 2025-12-12 18:25:53
CD70 drives cSCC growth by linking DNA damage response, inflammation, and tumor–stromal signaling
Tianshun Zhang, Qiushi Wang, Asad Khan, Chengcheng Hu, Emanuel Petricoin, Rebecca Morris, Sally Dickinson, and 3 more authors
Under Review
at
Articleposted 2025-12-08 12:53:16
Exhausted CD8⁺ T Cells Promote Ovarian Cancer Immunosuppression via CCL3-Driven M2 Macrophage Polarization
Wentao Yue, Yue Li, Jin Cheng, Fei Liu, Junjie Yi, Zhefeng Li, Yanheng Yu, and 2 more authors
Under Review
at
Articleposted 2025-12-08 07:08:34
T-cell engager bispecific antibodies enable T cells to eliminate Multiple Myeloma by targeting tumor CD38 in combination with PD-L1
Shanshan Luo, Chaofan Wang, Wanting Wang, Moran Wang, Mengling Yang, Jun Deng, Bahgat Fayed, and 6 more authors
Under Review
at
Articleposted 2025-12-05 08:59:14
USP5 regulates purine metabolism and represents a therapeutic target in esophageal cancer
Zigang Dong, Kexin Zhao, Lei Zhang, Mingyang Yan, Shaobo Fang, Zhenwei Wang, Yanming Song, and 8 more authors
Under Revision
at
Articleposted 2025-12-05 05:11:30
Neuromedin U promotes lung adenocarcinoma progression by enhancing nucleotide metabolism and potentiating fibrosis in the tumor microenvironment
Shih Sheng Jiang, Shih-Miao Li, Chi-Shuan Fan, Tzu-Yu Chen, Wen-Tsen Fang, Fang-Yu Tsai, Hui-Yu Jao, and 12 more authors
Under Review
at