Simple cell geometry metrics reveal cancer cell diversity and plasticity and guide combination therapy
Neuromedin U promotes lung adenocarcinoma progression by enhancing nucleotide metabolism and potentiating fibrosis in the tumor microenvironment
Metabolic molecular subtyping of ovarian cancer reveals the role of oleic acid-CD36 in facilitating cisplatin resistance
Surface-engineered dual drug-loaded tumor-targeted liposomal nanoparticles to overcome the therapeutic resistance in glioblastoma multiforme
SLC22A3 Regulates Ferroptosis in the Mesenchymal Subtype of Triple-Negative Breast Cancer by Modulating Histone H3K4 Serotonylation
FAK Inhibition Demonstrates Dual Effects of Tumor Suppression and Dormancy Induction Through Region-Specific COUP-TF1 Regulation
PHGDH inhibition overcomes dabrafenib resistance through metabolic rewiring in BRAF V600E anaplastic thyroid carcinoma
MET signaling drives acquired resistance to erdafitinib in muscle-invasive bladder cancer cells
UPR/ATF4/Noxa pathway over-activation through SERCA2 inhibition or ONC201 treatment combined with ABT-737 triggers apoptosis in chemoresistant ovarian cancer cells and patient-derived tumour organoids
Distinct RET Fusion Partner Genes in RET-Rearranged Spindle Cell Tumors Contribute to Varied Transformation Capacities